Congenital Nephrotic Syndrome - Finish Type

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Congenital Nephrotic Syndrome – Finish Type

INTRODUCTION Identification of the NPHS1 gene, which encodes nephrin, was followed by many studies demonstrating its mutation as a frequent cause of congenital nephrotic syndrome (CNS). While this gene is found in 98% of Finnish children with this syndrome, non-Finnish cases have lower level of incidence ranging from 39 to 80%. CASE REPORT This report describes the clinical presentation of a ...

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Congenital nephrotic syndrome, Finnish type

Keywords Disease name and synonyms Definition Incidence Clinical description Histology Treatment Etiology Antenatal diagnosis References Abstract The congenital nephrotic syndrome of the Finnish type is a hereditary disease with autosomal recessive inheritance. The gene frequency is approximately 1/200 in Finland. The disease is caused by mutations in the gene for nephrin, which is a key compon...

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Congenital Nephrotic Syndrome: A Cases Report

Congenital nephrotic syndrome (CNS) can be caused by neonatal infections and renal diseases that usually occur in early infancy. The most common CNS is the Finnish type, which is an autosomal recessively inherited disease characterized by intrauterine onset of massive proteinuria. In this study, we presented a preterm neonate confirmed as the first case of CNS in Iran by genetic study, who was ...

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Congenital nephrotic syndrome

CNS (Congenital nephrotic syndrome) is a disorder characterized by the presence of a nephrotic syndrome in the first three months of life. Different pathologies can cause this syndrome. In general, we can distinguish primary forms (sporadic and hereditary) and secondary forms (acquired and associated with other syndromes). The most common form is the Finnish CNS (CNF, congenital nephrotic syndr...

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Pathophysiology of Congenital Nephrotic Syndrome of the Finnish type

9 Review of the literature 11 1. Congenital nephrotic syndrome of the Finnish type (CNF, NPHS1) 11

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ژورنال

عنوان ژورنال: Medical Archives

سال: 2016

ISSN: 0350-199X

DOI: 10.5455/medarh.2016.70.232-234